The Brazilian Grand Prix (Portuguese: Grande Prêmio do Brasil) is a Formula One championship race which occurs at the Autódromo José Carlos Pace in Interlagos, a district in the city of São Paulo, Brazil.

A Brazilian Grand Prix was first held at Interlagos in 1972, although it was not part of the Formula One World Championship. The following year, however, the race was first included in the official calendar. In 1978 the Brazilian Grand Prix moved to Jacarepaguá in Rio de Janeiro, briefly returning to Interlagos for the next two seasons before becoming the sole host from 1981 onwards. In 1990 the Grand Prix returned to Interlagos, where it has stayed since. In 2005, for the first time, the Brazilian GP decided the World Championship, won by Fernando Alonso. On October 22, 2006, Felipe Massa won the Brazilian GP.

While the quality of its facilities are often questioned, the Interlagos circuit has created some of the most exciting and memorable races in recent Formula One history, and is regarded as one of the most challenging and exciting circuits on the F1 calendar. Along with Spa-Francorchamps, it is rare in that the circuit in its modern form is one of the few with a lengthy history in the sport not considered to have lost much of its mystique or challenge in its adaptation for the modern, much more safety-conscious era of 21st century Formula One.

Particularly memorable recent Brazilian Grands Prix include the 2003 race, which saw a maiden Grand Prix victory, highly unexpectedly, and amidst chaotic and unusual circumstances, for Jordan's Giancarlo Fisichella. Heavy rain before and during the race produced problems with tyre selection which caught out many teams, which allowed the weak Minardi team to have a real chance for victory the only time ever, because they were the only team who prepared to the rainfall, but their drivers were also soon out. And treacherous track conditions caused multiple drivers to spin out of the race, including then-reigning World Champion Michael Schumacher, ending a remarkable run of race finishes dating back to the German Grand Prix 2001. Amidst this, a number of drivers, including McLaren's Kimi Räikkönen and David Coulthard, led the race, and, when a heavy accident involving Renault's Fernando Alonso blocked the circuit and brought out the red flag, confusion reigned. Fisichella led the race at the time, having just overtaken Räikkönen; however, it was the Finn who was declared the race winner under the countback rule, which stipulates that the race result in such circumstances is taken from the running order two laps prior to the race being stopped. This decision was overturned days later in the FIA Court of Appeal in Paris after new evidence came to light which proved that Fisichella had crossed the finish line in the lead for a second time before Alonso's accident, and therefore was the rightful winner.

The 2001 Grand Prix was notable for marking the explosive arrival of Juan Pablo Montoya onto the Formula One scene. The Colombian driver stunningly muscled his way past Michael Schumacher early on and led easily until an incident in which Arrows' Jos Verstappen ran into the back of his Williams-BMW and ended his race. Montoya did eventually lay to rest the ghost of this event by winning the 2004 race in his final Grand Prix for Williams before moving to McLaren, holding off his future team-mate Kimi Räikkönen to take a hard-fought victory.

Fernando Alonso became the youngest ever Formula One World Champion at the 2005 Brazilian Grand Prix, his third place behind winner Juan Pablo Montoya and championship rival Kimi Räikkönen enough to clinch the title with two races remaining.

For 2006 the Brazilian Grand Prix, as in 2004, was moved to the prestigious position of hosting the final round of the season, in what was Michael Schumacher's farewell to Formula One. Starting from 10th position on the grid, Schumacher did an astonishing job on his last race. He fell to 19th position on the ninth lap due to a flat tyre caused by a minor collision with Giancarlo Fisichella when the former was trying to overturn the latter. After pitting for a new tyre he returned to the race, just in front of leader Massa, so almost being overlapped, passing several drivers to take the checkered flag in fourth place, after a dazzling passing manoeuvre on Kimi Räikkönen. His performance was not enough to give 'Schumi' his eighth trophy, as Fernando Alonso, who needed only one point to become World Champion again, finished in second place. Brazilian Felipe Massa took pole position and led the race from start to finish for the second victory of his career and celebrations from his Brazilian supporters.

In March 2008, the mayor of Sao Paulo announced that he had signed a new deal with Bernie Ecclestone to continue the holding of the Brazilian Grand Prix. This deal allows the Brazilian race to be on the calendar until 2015. With this, Interlagos is set for major improvements in its pit and paddock facilities.